If the same version of the software is reinstalled on the same machine and the hard disk is not reformatted prior to reinstalling, the software will remain activated. Reactivation will be required if the hard disk is reformatted and the software is reinstalled. This is because the software's activation status is stored on the hard drive and reformatting the hard drive erases that status.
If you want to reinstall your Windows, you can backup the key.bin file for later restore.
Windows 2000/XP key.bin location: C:\Documents and Settings\All Users\Application Data\MyUSBOnly\key.bin
Windows Vista key.bin location: C:\ProgramData\MyUSBOnly\key.bin